File:1-s2.0-S1542012416000100-gr3.jpg

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English: Figure 3. Mechanism of action (MOA) of lifitegrast at the cellular level. ICAM-1 = intercellular adhesion molecule 1; LFA-1 = lymphocyte function-associated antigen 1; mAPC = mature antigen-presenting cell; TH = T helper cell. Disclaimer: this figure illustrates the current understanding of the MOA of lifitegrast based on completed preclinical and clinical studies. Additional studies in the posterior ocular tissues and vascular system are required to further elucidate the MOA of lifitegrast.
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Source https://www.sciencedirect.com/science/article/pii/S1542012416000100?via%3Dihub
Author Victor L. Perez , Stephen C. Pflugfelder , Steven Zhang , Amir Shojaei , Reza Haque

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