File:Adult granulosa cell tumor of the ovary (Radiopaedia 64991-74394 10x H&E 1).jpg

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Summary:

Description
  • Radiopaedia case ID: 64991
  • Image ID: 45219119
  • Plane projection: 10x
  • Aux modality: H&E
  • Study findings: Macroscopically: the tumor was well-encapsulated, measuring 5 x 5.2 cm, with a smooth outer surface, heterogeneous in appearance: whitish solid with cystic components containing hemorrhage. Microscopically: it appears as a well-defined, encapsulated, tumoral  proliferation composed  of cell layers, multinodular structures, trabecular patterns and some follicular territories of variable size delineating fibro-hyaline structures corresponding to the "Call-Exner bodies" Immunohistochemistry: -vimentin: positive. -CK7 and CK20: shows negativity of the proliferation -actin: positive -AE 1 / AE 3  shows a positive marking (focally) -EMA: negative -Inhibin: positive, calretinin: positive
  • Modality: Pathology
  • System: Gynaecology
  • Findings: A well-defined lobulated right ovarian mass (5.5 x 5 x 4.5 cm) of intermediate signal intensity on T1WI, intermediate to high signal intensity on T2WI, containing areas of high signal on T1WI and T2WI with hemosiderin sediment on T2WI (hemorrhage within locules). The solid component shows moderate and heterogeneous enhancement following IV contrast. The DWI / ADC show restricted diffusion. Left ovary and uterus appear normal with no significant endometrial thickening (thickness = 7 mm) No pelvic lymphadenopathy or effusion is seen.
Date Published: 8th Jan 2019
Source https://radiopaedia.org/cases/adult-granulosa-cell-tumour-of-the-ovary
Author Dr Ammar Haouimi
Permission
(Permission-reusing-text)		 http://creativecommons.org/licenses/by-nc-sa/3.0/

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Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)

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current05:32, 27 April 2021Thumbnail for version as of 05:32, 27 April 20211,280 × 1,024 (269 KB)Fæ (talk | contribs)Radiopaedia project rID:64991 (batch #1415-3 C1)

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