File:Atypical meningioma with skull invasion (Radiopaedia 34357-35748 A 1).png

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Atypical_meningioma_with_skull_invasion_(Radiopaedia_34357-35748_A_1).png ‎(720 × 540 pixels, file size: 970 KB, MIME type: image/png)

Summary:

Description
  • Radiopaedia case ID: 34357
  • Image ID: 11192728
  • Study description: Histology
  • Study findings: The patient underwent to a surgical resection. MICROSCOPIC DESCRIPTION: The sections show a meningioma with increased cellularity. The tumor forms solid sheets as well as scattered whorls. The tumor cells have enlarged and mildly pleomorphic nuclei with focal prominent nucleoli. There are up to 16 mitoses per 10 high power fields. Areas of necrosis are seen. Cerebral cortex is present and there is no evidence of brain invasion. The tumor invades through the dura into the skull bone. It involves the entire thickness of the bone through the cortex and it is 0.1mm from the outer periosteum. The tumor involves the circumferential radial bony margin. There is no evidence of malignant change. The features are those of atypical meningioma. The Ki-67 index is about 20%. About 10% of the tumor cells are weakly progesterone receptor positive. DIAGNOSIS: Atypical meningioma with full thickness invasion into skull bone (WHO Grade II).
  • Modality: Pathology
  • System: Central Nervous System
  • Findings: Large extra-axial mass, both solid and cystic, with homogeneous enhancement, localized in the right posterior frontal region with a large dural attachment and adjacent skull erosion. There is local mass effect.
Date Published: 17th Feb 2015
Source https://radiopaedia.org/cases/atypical-meningioma-with-skull-invasion
Author RMH Neuropathology
Permission
(Permission-reusing-text)		 http://creativecommons.org/licenses/by-nc-sa/3.0/

Licensing:

Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)

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