File:Clear cell meningoma - lumbar spine (Radiopaedia 60116-78655 PAS 1).jpg

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Description	Radiopaedia case ID: 60116 Image ID: 49642887 Aux modality: PAS Study findings: Paraffin sections show a moderately cellular dural-based tumor. Tumor cells have moderately pleomorphic round and oval nuclei with vesicular chromatin and a moderate amount of clear cytoplasm containing varying amounts of glycogen. Cell boundaries are poorly demarcated. There is a discernible syncytial arrangement of tumor cells in many areas. No mitotic figures or areas of necrosis are identified. Immunohistochemistry shows strong membrane staining in tumor cells for epithelial membrane antigen (EMA) (not shown) and somatostatin receptor (SSR2). There also patchy moderate nuclear staining for progesterone receptor (PgR) (not shown). The features are of clear cell meningioma (WHO Grade II). The topoisomerase labeling index is approximately 8%. FINAL DIAGNOSIS: Clear cell meningioma (WHO Grade II). Modality: Pathology System: Spine Findings: Intrathecal slightly hyperdense mass is seen at the L3 and L4 level without calcification or bony remodeling.
Date	Published: 19th Jun 2019
Source	https://radiopaedia.org/cases/clear-cell-meningoma-lumbar-spine
Author	Frank Gaillard
Permission (Permission-reusing-text)	http://creativecommons.org/licenses/by-nc-sa/3.0/

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	16:44, 25 August 2021		1,030 × 1,030 (200 KB)	Fæ (talk \| contribs)	Radiopaedia project rID:60116 (batch #8322-3 C1)

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