File:Clival chordoma invading the hypoglossal canal (Radiopaedia 48850-53976 A 1).png

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Clival_chordoma_invading_the_hypoglossal_canal_(Radiopaedia_48850-53976_A_1).png(600 × 450 pixels, file size: 669 KB, MIME type: image/png)

Summary:

Description
  • Radiopaedia case ID: 48850
  • Image ID: 25948437
  • Study findings: MICROSCOPIC DESCRIPTION: 1&2. Sections show a moderately cellular tumor, together with fragments of bone. The tumor is composed of cells with abundant clear to vacuolated cytoplasm set within myxoid stromal material. Tumor cells contain hyperchromatic, angulated nuclei with bland chromatin and inconspicuous nucleoli. No necrosis or mitosis are seen. There are areas of hemorrhage with hemosiderin laden macrophages and immature woven bone, consistent with remodeling. Immunohistochemical results show tumor cells stain: CKAE1/3+, EMA+ and S100+; consistent with chordoma. DIAGNOSIS: 1&2. Brain, posterior fossa lesion: Chordoma. Images and report courtesy from the Royal Melbourne Hospital Pathology Department.
  • Modality: Pathology
  • System: Central Nervous System
  • Findings: Erosive bone lesion involving the inferior most aspect of the clivus, at the region of the Basion/foramen magnum, with sclerotic and regular margins. Its soft tissue component that does not cause mass effect over the medulla oblongata. The remainder of the brain is unremarkable. Further evaluation with an MRI study is recommended.
Date Published: 1st Nov 2016
Source https://radiopaedia.org/cases/clival-chordoma-invading-the-hypoglossal-canal
Author Bruno Di Muzio
Permission
(Permission-reusing-text)
http://creativecommons.org/licenses/by-nc-sa/3.0/

Licensing:

Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)

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current07:58, 26 August 2021Thumbnail for version as of 07:58, 26 August 2021600 × 450 (669 KB) (talk | contribs)Radiopaedia project rID:48850 (batch #8380-1 A1)

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