File:DDDT-137783-F01 (cropped).jpg
Jump to navigation
Jump to search
DDDT-137783-F01_(cropped).jpg (538 × 337 pixels, file size: 21 KB, MIME type: image/jpeg)
Summary
Description |
English: Figure 1 Mode of action of CDK4/6 inhibitors.
Notes: Palbociclib, ribociclib and abemaciclib inhibit the complex CDK4/cyclin D1, responsible for the phosphorylation and inhibition of the Rb tumor-suppressor gene’s product. When Rb is phosphorylated, the cell proceeds from G1 to Phase S of the cell cycle, replicating DNA and preparing for mitosis. Abbreviation: Rb, retinoblastoma. |
Date | |
Source | https://www.dovepress.com/abemaciclib-a-cdk46-inhibitor-for-the-treatment-of-hrher2-advanced-bre-peer-reviewed-fulltext-article-DDDT |
Author | Corona SP , Generali D |
Other-versions | Lua error in Module:Autotranslate at line 77: No fallback page found for autotranslate (base=Extracted from, lang=⧼lang⧽). |
Licensing
English: This file is licensed CC BY-NC 3.0
This file was uploaded with UploadWizard.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 07:37, 22 March 2024 | 538 × 337 (21 KB) | Doc James (talk | contribs) | File:DDDT-137783-F01.jpg cropped 3 % horizontally, 31 % vertically using CropTool with precise mode. |
You cannot overwrite this file.
File usage
The following page uses this file: