File:Fmicb-09-01879-g001.jpg
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Summary
Description |
English: Pulmonary inflammation is induced by HTLV-1 cells infected by HTLV-1 (T CD4+, T CD25+, and Lung Epithelial cells). MIP-1α chemokine recruits and activates inflammatory cells to the lungs (HTLV-1 specific T CD8+ cells) expressing inflammatory cytokines (IL-1α, IL-1, IL-2, IL-6, IL-8, and TNF). There is an increase in IP-10, a chemokine that plays a key role in the pathogenesis of pulmonary fibrosis. Associated with this, ICAM-1 acts by facilitating neutrophil adhesion to pulmonary epithelial cells and potentiating local chronic inflammation. The result is the development of Alveolitis and Fibrosis. |
Date | |
Source | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103007/ |
Author | Apio R. N. Dias,Luiz F. M. Falcão,Aline S. C. Falcão, Valéria M. F. Normando, Juarez A. S. Quaresma |
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English: This file is licensed CC BY-NC 4.0
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current | 18:18, 18 March 2023 | 785 × 762 (117 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Apio R. N. Dias,Luiz F. M. Falcão,Aline S. C. Falcão, Valéria M. F. Normando, Juarez A. S. Quaresma from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103007/ with UploadWizard |
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