File:Ijms-22-06600-g001-550.webp
Jump to navigation
Jump to search
Ijms-22-06600-g001-550.webp (357 × 550 pixels, file size: 26 KB, MIME type: image/webp)
Summary
Description |
English: Figure 1. Altered cholesterol trafficking in Niemann–Pick disease type C. (A) In normal conditions, lipoprotein cholesterol particles bind to cell surface receptors and are internalized in the late endosome/lysosome system. In the presence of NPC1 and NPC2 proteins, unesterified cholesterol is transported from the late endosomal/lysosomal system to the Golgi complex and endoplasmic reticulum, where it is processed and used for other reactions. (B) In the absence of NPC1 or NPC2, unesterified cholesterol accumulates in the late endosomal/lysosomal system, resulting in deficiencies in the intracellular compartments for which it was intended. |
Date | |
Source | https://www.mdpi.com/1422-0067/22/12/6600 |
Author | Ida Cariati,Laura Masuelli ,Roberto Bei ,Virginia Tancredi,Claudio Frank ,Giovanna D’Arcangelo |
Licensing
{{subst:Custom license marker added by UW}} https://creativecommons.org/licenses/by/4.0/ Attribution 4.0 International (had to bring to NCC as Commons would not upload)
This file was uploaded with UploadWizard.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 19:28, 16 November 2023 | 357 × 550 (26 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Ida Cariati,Laura Masuelli ,Roberto Bei ,Virginia Tancredi,Claudio Frank ,Giovanna D’Arcangelo from https://www.mdpi.com/1422-0067/22/12/6600 with UploadWizard |
You cannot overwrite this file.
File usage
There are no pages that use this file.