File:Images large 10.1177 20420188211058323-fig3.jpg
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| Description |
English: Figure 3. The mechanism of action of lomitapide. MTP is required for assembly and secretion of apoB-containing lipoproteins in the liver (apoB100) and intestine (apoB48). After production in the liver, VLDL is released into the plasma, where the TG content of the VLDL is hydrolyzed into free fatty acids, eventually forming LDL. By inhibiting MTP, lomitapide reduces the production and release of VLDL and LDL levels in plasma while at the same time reducing TG levels by reducing intestinal chylomicron formation. |
| Date | |
| Source | https://journals.sagepub.com/doi/10.1177/20420188211058323 |
| Author | Bhuvana Sunil, Christy Foster, Ambika P. Ashraf and |
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| current | 16:14, 5 May 2024 | | 1,661 × 623 (512 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Bhuvana Sunil, Christy Foster, Ambika P. Ashraf and from https://journals.sagepub.com/doi/10.1177/20420188211058323 with UploadWizard |
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