File:PMC4833782 415 2015 7905 Fig1 HTML.png
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PMC4833782_415_2015_7905_Fig1_HTML.png (512 × 195 pixels, file size: 108 KB, MIME type: image/png)
Summary
Description |
English: Fig1: To analyze the cerebral blood glucose utilization during an actual VM attack a FDG-PET was performed in a 35-year-old patient suffering from VM according to the consensus criteria [8, 9] (ECAT Exact PET Scanner, Siemens/CTI, Knoxville, USA, with a 18F-fluorodeoxyglucose [FDG]-tracer in a three-dimensional acquisition mode). During the attack the patient presented with a central positional nystagmus beating oblique (up- and leftward) and increasing in different head/body positions (supine, left ear down, right ear down). Both, nystagmus and vertiginous sensation, persisted for 72 h and resolved spontaneously without any ongoing vestibular or ocular motor dysfunction. In addition, a structural T1-weighted MRI (MPRAGE sequence, 180 slices, slice thickness = 1 mm, image matrix = 2562, TR = 9.7 ms, TE = 4 ms) was acquired in a clinical 1.5 T scanner (Siemens Vision, Erlangen, Germany). The PET image was spatially normalised using the structural MRI data and a proportional scaling was performed to adjust for differences in tracer dosage and uptake time. A two-sample t test was computed with respect to a healthy, age-matched reference sample (n = 12) acquired on the same scanner under identical conditions (supine, eyes closed). During the attack the patient showed an increased cerebral glucose metabolism bilaterally in the ventral-anterior thalamus compared to healthy volunteers at rest (p < 0.001 uncorrected). The thalamic response was localized to the prefrontal thalamic projection zone [87]. The scale reflects the z score (personal communication: C. Best, Marburg, and P. zu Eulenburg, Mainz, Germany) |
Date | |
Source | https://openi.nlm.nih.gov/detailedresult?img=PMC4833782_415_2015_7905_Fig1_HTML&query=Eulenburg%20disease&it=xg&req=4&npos=4 |
Author | Dieterich M, Obermann M, Celebisoy N |
Licensing
{{subst:Custom license marker added by UW}} https://creativecommons.org/licenses/by/4.0/ Attribution 4.0 International (CC BY 4.0)
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current | 19:53, 28 October 2022 | 512 × 195 (108 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Dieterich M, Obermann M, Celebisoy N from https://openi.nlm.nih.gov/detailedresult?img=PMC4833782_415_2015_7905_Fig1_HTML&query=Eulenburg%20disease&it=xg&req=4&npos=4 with UploadWizard |
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