File:1-s2.0-S1930043323001425-gr3.jpg
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1-s2.0-S1930043323001425-gr3.jpg (670 × 439 pixels, file size: 72 KB, MIME type: image/jpeg)
Summary
Description |
English: Fig. 3. Graphical illustration of the downstream mechanism of Stx-induced endothelial injury in brain blood vessels. TNF induces Gb3 upregulation by endothelial cells, which subsequently increases the affinity of these cells to Stx (1). Stx effect on endothelial cells involves a DNA damage response (2), which results in the activation of caspase enzymes (3) with subsequent apoptosis (4). Stx: shiga toxin, TNF: tumor necrosis factor, Gb3: globotriaosylceramide. |
Date | |
Source | https://www.sciencedirect.com/science/article/pii/S1930043323001425 |
Author | Mansour MA, Khalil DF, Hasham MA, Youssef A, Rashad M, Awadallah M, Ali H. |
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English: This file is licensed CC BY-NC-ND 4.0
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current | 00:07, 11 April 2024 | 670 × 439 (72 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Mansour MA, Khalil DF, Hasham MA, Youssef A, Rashad M, Awadallah M, Ali H. from https://www.sciencedirect.com/science/article/pii/S1930043323001425 with UploadWizard |
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