File:Kabir Rotor Syndrome.jpg
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Summary
Description |
English: Metabolic pathway for bilirubin in the hepatocyte. Bilirubin-G corresponds to bilirubin glucuronate, where the donor is uridine diphosphate glucuronic acid (UDP-GA). This is catalyzed by the enzyme uridine diphosphate-glucuronyltransferase (UGT1A1). Gilbert and Crigler-Najjar syndrome are associated with decreases in UGT1A1 activity. Glutathione-S-transferase (GST) is a carrier protein that assists with bilirubin uptake into the cytosol and may be implicated in Rotor syndrome |
Date | |
Source | https://www.ncbi.nlm.nih.gov/books/NBK562171/ |
Author | Jenish Bhandari; Pawan K. Thada; Deepak Yadav. |
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English: This file is licensed CC BY-NC-ND 4.0
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current | 20:09, 13 April 2023 | 680 × 947 (80 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Jenish Bhandari; Pawan K. Thada; Deepak Yadav. from https://www.ncbi.nlm.nih.gov/books/NBK562171/ with UploadWizard |
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